Arsenal are now in pole position to finish in the top four this season after a run of seven wins in their previous nine.
However, their away form continues to hinder, winning just five of 14 on the road, and Unai Emery knows Tottenham, Chelsea and Manchester United will pounce on any slip-up.
Everton, who fancy themselves as top-six gatecrashers, sit 10th after recording back-to-back wins for only the second time this season, and will be up for proving their credentials against the Gunners.
Everton XI: Pickford, Coleman, Keane, Zouma, Digne, Andre Gomes, Gueye, Richarlison, Sigurdsson, Bernard, Calvert-Lewin
Subs: Baines, Jagielka, Walcott, Tosun, Stekelenburg, Davies, Lookman
Arsenal: Leno, Mustafi, Sokratis, Monreal, Maitland-Niles, Elneny, Guendouzi, Kolasinac, Ozil, Mkhitaryan, Lacazette
Subs: Cech, Lichtsteiner, Iwobi, Suarez, Jenkinson, Ramsey, Aubameyang