Arsenal are sweating on the fitness of Alexandre Lacazette after he missed the 2-1 win at Bournemouth with a minor groin complaint. Head coach Unai Emery will be keen for him to feature this weekend.
Nacho Monreal, Konstantinos Mavropanos and Danny Welbeck remain sidelined, while Mesut Ozil will be pushing for a recall after sitting on the bench at the Vitality Stadium.
Possible line-up: Leno; Mustafi, Sokratis, Holding,; Bellerin, Xhaka, Torreira; Kolasinac; Iwobi, Ozil; Aubameyang.
For Tottenham, Vincent Janssen, Mousa Dembele, Davinson Sanchez and Victor Wanyama are all out injured. Kieran Trippier and Danny Rose should both be available after recent injuries.
Possible line-up: Lloris; Aurier, Alderweireld, Vertonghen, Rose; Sissoko, Dier; Son, Alli, Eriksen; Kane